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  • A point mutation is a change in a single nucleotide in DNA.
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    Substitution mutations are situations where a single nucleotide is changed into another.

  • Point mutations may have a wide range of effects on protein function (Figure 11.
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    Crohn's disease.

  • A substitution mutation occurs when one base pair is substituted for another.
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    Hence, it does not change the final protein.

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    This change.